D-MANOZINN® (d-mannose) is a dietary supplement registered in Serbia as foods for special medical purposes containing pure d-mannose, monosaccharides, free from any added substances.
D-mannose has been used globally for more than 30 years as the natural product for elimination of E. coli from the urinary tract. The greatest number of patients was more than pleased with the use of d-mannose without any side effects, which is the main argument in favour of d-mannose.
The package of D-MANOZINN® contains 54 g of powder dosed with a spoon provided in a pack. Levelled off spoon of D MANOZINN® powder contains 1.8g of d-mannose. A package of D-MANOZINN® contains 30 doses of powder.
AVAILABLE IN ALL WELL SUPPLIED PHARMACIES ALL OVER SERBIA.
Urinary tract infections occur very often. One out of five women on average suffers from UTI, with at least one urinary infection in life, and this kind of infection is most frequently a recurrent one.
Bacterium E. coli is most frequently (in about 90%) the cause and reason for the occurrence of urinary tract infections.
This bacterium (E. coli) is a normal inhabitant of the colon, but it will cause the urinary tract infection if it manages to find its way to the urinary tract through the urethra. The reason why these infections are far more common in women than in men is that the urethra is shorter in women than in men and it is closer to the anus.
Groups with the highest risk of developing the infection:
Sexually active women
Frequent sexual intercourses lead to irritation of mucous membrane facilitating the bacteria to pass from the environment into the urinary tract.
This kind of infection is not accidental, it is called the “honeymoon cystitis”
Menopausal and post-menopausal women:
Changes in hormonal levels lead to increased risk of urinary infections.
The hormone progesterone relaxes the muscles of the urinary tract. In such a situation, bacteria penetrate more easily the urinary tract from the environment through the urethra.
Women with weakened immune system:
Stress, medicines or colds, are all, for example, reasons for weakening of our immune system.
Urinary tract infections and fight between good and evil bacteria.
Once they arrive in the bladder, bacteria are capable of causing symptoms known as UTI – urinary tract infection. Bacteria bind to the bladder wall, which on the other hand, leads to irritation and inflammation.
All this is the reason for the pain and discomfort that you feel when you suffer from this unpleasant condition.
Factors increasing the risk of developing urinary tract infections:
Dehydration due to reduced water intake, resulting in reduced urine excretion, meaning that the ability of efficient washing out of “bad bacteria” by bigger (required) stream i.e. urine volume is also reduced.
Reduced number of “good” bacteria in urinary tract most frequently caused by previous use of antibiotics, resulting in reduced protective effect of these bacteria.
Postponing urination after sex
Use of the diaphragm and spermicide for birth control
Menopause (protective epithelium of the bladder and urinary tract becomes weaker and more susceptible to infections)
Pain is caused by the smallest quantity of urine as it passes through the urethra
Frequent and sudden need to urinate (most frequently during the night)
Abdominal pain (lower abdomen) and/or low back pain
Fever, chill and/or nausea*
Turbid or darker urine than usual (this is often followed by characteristic unpleasnat smell of urine)
Blood can occur in urine in about 30% of cases
If the symptoms persist for more than 3 to 5 days and there is no significant improvement, the doctor has to be consulted.
* In case of this symptom consult your doctor immediately.
How to prevent a urinary infection?
Protection from urinary infections
Urinary tract has several mechanisms to reduce the possibility of infection by pathogens such as E. coli, the most important are the following:
An adequate flow of urine
Absence of “friendly“ or “good” bacteria known also as probiotics which should normally inhabit the urinary tract and vaginal mucosa and thus represent our “internal troops” preventing “bad” or “evil” bacteria to bind to the walls of these organs.
If this defense is compromised, disabled, issuficiently strong, a bladder infection will develop (infection of urinary tract).
By specified actions you can reduce the number of recurring infections or even completely prevent their appearance:
Take roughly 2 litres of fluid each day out of which about 1.5 l of urine is excreted.
Urinate as soon as possible after each sexual intercourse.
Take care that your feet do not get cold (beware of hypothermia). Change wet clothes as soon as possible.
When you feel the urge to urinate, do not postpone it.
After defecation wipe yourself from the front (from vagina) to the back (towards anus) and not the vice versa.
Do not exaggerate in maintaining hygiene, do not wash your genital area too often, especially not with strong soaps and disinfectant agents or lotions, because acidic protective layer on the mucous membrane can be easily damaged.
What to do in case of urinary infection?
Frequent irritation caused by urinary tract infection disappears by itself without any special treatment only by intake of large quantities of water.
If infection lasts for 2 days or more, it is of crucial importance to start the treatment either with antibiotics or with efficient natural products used for solving the problems of urinary tract infections.
It is important to know that bacteria causing these infections such as E.coli can continue to travel “upstream” through the urinary tract to the kidneys, which then can cause a kidney infection which makes the situation far more serious.
Urinary tract infections treatments
Antibiotic therapy is the most frequent and most common medical treatment for UTI. It aims to destroy bacteria and usually takes 5-7 days.
Antibiotic therapy usually includes also side effects.
It primarily reduces the number of “good” bacteria which can facilitate the occurrence of new infections in the future since the number of “internal troops” fighting “the enemy bacteria” is also reduced.
It is of particular importance to emphasize that resistance to antibiotics due to their excessive use means that they cannot be efficient any more when required.
D-MANOZINN relives the urinary tract from bacterium E coli. When urine gets saturated with molecules of d-mannose, bacteria bind more easily and faster to d-mannose molecules than to the urinary tract wall. Once the bacteria have bound themselves to D-MANOZINN® molecule, they get expelled from the body via urine.
Quick and easy cure of discomfort
Does not cause resistance
No side effects
Suitable for children, pregnant women and breast-feeding women
Suitable for diabetics with control of glycemia
First and only product in Serbia which contains d-mannose
How does D-MANOZINN® work?
Urine volume and “good” bacteria normally living in urinary tract most frequently prevent bacterium E. coli from developing.
In cases when urine volume is insufficient – in case of dehydration or when the bladder is pressed or crushed as in the case of pregnancy, urine will be kept for too long giving a chance to bacteria to develop, causing thus the irritation and inflammation.
The bacteria that most commonly leads to inflammation of the bladder and urinary tract infection is the bacterium E. coli. This bacterium has finger-like extensions, fimbriae, at its surface which it uses to bind to the urinary tract wall in humans starting thus the infection.
PHASE 1: Bladder infection is usually caused by the bacterium E. coli that comes from the digestive tract.
PHASE 2: The protective layer covering (protecting) the cell lining of the bladder is made up of molecular structure, which includes a large number of sugar molecules (endogenous d-mannose). The bacterium E. coli (which nevertheless loves sugar) primarily binds to these molecules, after which the inflammation process starts which sets our immune system in motion.
PHASE 3: Administering D-MANOZINN® will enable the presence of greater quantities of d-mannose molecules in urine. D-mannose is extremely poorly metabolized, therefore most of the administered d-mannose is excreted in urine unchanged.
PHASE 4: D-mannose binds to (gets attached to) fimbriae (small extensions) of bacteria which leads to inflammation (90% E. coli). D-mannose thus prevents bacteria from binding to the wall of our urinary tract and enables easy and fast elimination of bacteria (their washing down) into the environment via urine.
So, use D-MANOZINN®, because
Enables easy and fast elimination of
E. Coli from the urinary tract.
D-mannose has been used worldwide for more than 30 years as a natural product for elimination of the bacterium E. coli from the urinary tract. The largest number of patients was very pleased with the use of d-mannose. D-mannose has no side effects which is the main argument in favour of d-mannose.
The study demonstrated that d-mannose is equally efficient as antibiotic Nitrofurantoin. *
D-MANOZINN® helps in preventing cystitis
It would be ideal to take D-MANOZINN® before or during certain situations that can represent a typical trigger of cystitis:
Prevention of honeymoon cystitis
(1-2 spoons before and after a sexual intercourse)
Prevention treatment over a longer period in case of recurrent cystitis.
Preventive use is very well documented. It has been stressed out that there is no need for antibiotics if effective prophylaxis with d-mannose has been undertaken. Patients also primarily insist on not having the need for an antibiotic. There is no interaction with d-mannose in women that use a lot of medicines.
* Kranjcec B. et al .: D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial; World J Urol (2014) 32: 79-84D- in this context mannose is as efficient as an antibiotic*.